The 31-year-old missed the first T20I on Tuesday after sustaining a contusion to his left big toe during training.
Subsequent scans on Wednesday revealed a fracture and he will consult with a specialist orthopaedic surgeon to determine the recovery period.
Northerns Titans all-rounder Dayyaan Galiem has been named as Nortje’s replacement for the
remaining two T20Is, in Centurion on Friday and the Wanderers on Saturday.
Photo: Philip Brown/Gallo Images